This activity is a capstone experience that illustrates how basic science can be used to advance medicine and public health. Having established a base of knowledge about botulinum toxin, students simulate the processes by which a biotechnology company interested in developing botulinum toxin into a molecular tool for disease prevention or treatment would proceed with research and development. Students will review basic science and public health needs, use risk-benefit and cost-benefit analyses, develop proposals and evaluate their proposals from the point of view of a scientific advisory board.
By the completion of this activity students should be able to:
- Identify the functional domains of botulinum toxin.
- Comprehend the molecular mechanisms of immunity
and immunotoxin therapy.
- Appreciate the complexities of the drug development
process.
- Examine public health problems using a business
perspective.
- Recognize the compromises that often accompany
public health measures.
- Communicate their ideas in a more clear and cogent manner.
This Activity will demonstrate the potential conflicts
between the pharmaceutical and public health sectors
and introduce students to the business and safety
interests of medicinal science. The Activity contains
one Assignment and a set of Teaching Notes.
For a downloadable/printable version in PDF format of these pages visit Core Materials
Return to Top

