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Activity 6
Chimeric Botulinum Toxin Therapeutics
 
Activity 6: Chimeric Botulinum Toxin Therapeutics

This activity is a capstone experience that illustrates how basic science can be used to advance medicine and public health. Having established a base of knowledge about botulinum toxin, students simulate the processes by which a biotechnology company interested in developing botulinum toxin into a molecular tool for disease prevention or treatment would proceed with research and development. Students will review basic science and public health needs, use risk-benefit and cost-benefit analyses, develop proposals and evaluate their proposals from the point of view of a scientific advisory board.

By the completion of this activity students should be able to:

  • Identify the functional domains of botulinum toxin.
  • Comprehend the molecular mechanisms of immunity and immunotoxin therapy.
  • Appreciate the complexities of the drug development process.
  • Examine public health problems using a business perspective.
  • Recognize the compromises that often accompany public health measures.
  • Communicate their ideas in a more clear and cogent manner.

This Activity will demonstrate the potential conflicts between the pharmaceutical and public health sectors and introduce students to the business and safety interests of medicinal science. The Activity contains one Assignment and a set of Teaching Notes.

Assignment
Teaching Notes


For a downloadable/printable version in PDF format of these pages visit Core Materials

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